| Day | Week | Home | Result | Away |
|---|---|---|---|---|
| 2025-03-15 | 1 | Seattle Reign | 1 - 1 | Gotham FC |
| 2025-03-22 | 2 | North Carolina Courage | 1 - 2 | Seattle Reign |
| 2025-03-30 | 3 | Angel City | 2 - 1 | Seattle Reign |
| 2025-04-12 | 4 | Seattle Reign | 0 - 1 | Orlando Pride |
| 2025-04-18 | 5 | Seattle Reign | 1 - 0 | Portland Thorns |
| 2025-04-26 | 6 | Bay FC | 1 - 1 | Seattle Reign |
| 2025-05-02 | 7 | Seattle Reign | 1 - 0 | Kansas City Current |
| 2025-05-11 | 8 | Seattle Reign | 0 - 1 | Houston Dash |
| 2025-05-17 | 9 | Racing Louisville | 0 - 1 | Seattle Reign |
| 2025-05-23 | 10 | Seattle Reign | 1 - 2 | Washington Spirit |
| 2025-06-06 | 11 | San Diego Wave | 1 - 2 | Seattle Reign |
| 2025-06-14 | 12 | Chicago Stars | 2 - 2 | Seattle Reign |
| 2025-06-21 | 13 | Utah Royals | 1 - 4 | Seattle Reign |
| 2025-08-01 | 14 | Seattle Reign | 2 - 0 | Angel City |
| 2025-08-10 | 15 | Portland Thorns | 4 - 2 | Seattle Reign |
| 2025-08-18 | 16 | Seattle Reign | 3 - 3 | Chicago Stars |
| 2025-08-24 | 17 | Houston Dash | 1 - 1 | Seattle Reign |
| 2025-08-29 | 18 | Seattle Reign | 0 - 0 | San Diego Wave |
| 2025-09-07 | 19 | Washington Spirit | 2 - 0 | Seattle Reign |
| 2025-09-16 | 20 | Seattle Reign | 1 - 0 | Racing Louisville |
| 2025-09-20 | 21 | Kansas City Current | 2 - 0 | Seattle Reign |
| 2025-09-28 | 22 | Seattle Reign | 2 - 1 | North Carolina Courage |
| 2025-10-05 | 23 | Gotham FC | 0 - 0 | Seattle Reign |
| 2025-10-10 | 24 | Seattle Reign | 1 - 1 | Bay FC |
| 2025-10-17 | 25 | Seattle Reign | 2 - 1 | Utah Royals |
| 2025-11-02 | 26 | Orlando Pride | 1 - 1 | Seattle Reign |
Seattle Reign
2025シーズン